Figured I'd chime in again since I changed my pocketshield settings recently.
Here's what I used to have it set to:
Unlock with slide and stylus out
Slide to answer/ignore with pocketshield dialer (removed the default dialer).
It worked almost perfectly - unlocking without there being a call was flawless, but sometimes (emphasis on sometimes) wouldn't slide when trying to answer/ignore - nothing hitting the talk/end hard keys couldn't fix. For the record, I never had a missed call because I was locked out of answering.
Here are my new settings (thanks to shadowdrake for pointing this one out):
Restored the default dialer (with s2a)
Left unlock with slide/stylus out as is
Set pocketshield to unlock on incoming call (s2a shows up perfectly)
Now I have ZERO lockups.
Granted, its not as customizable as s2u2, but I'd rather have a simplistic lock mechanism that just works 100% of the time rather than have something with a million customization options and have it either be really laggy or lock you out of your phone. Just my 0.02 - I know you ppcgeeks love your customization