Misaligned Digitizer/ Touch Screen

[nikonx]

Recently, I have had problems with the touch screen becoming misaligned so that when I touch one place, it activates something near it. I have tried realigning it using the control panel, which works for a little while but eventually becomes messed up again. Is this a hardware or software problem? or could it be a combo of both?

I am running Big J's latest rom with no extra software.