I'm having the same problem. Here's the weird part: it was working fine with both 5 and 6 tab HTC Home plugin versions. I then installed another program that led to a hard reset (

). I thought, no worries, i had neatly stored all my .CABs and other PPC files on my PC.
Well, I've installed and uninstalled and reinstalled and whenever I "Save Changes" it hangs and I even have to reinstall HTC Home plugin.
I *know* it's the same versions that had worked before.
Possibly related: TaskManager v2.9 hangs when trying to list processes and this was working fine pre-Hard Reset too... could it be something with accessing/affecting running programs? Why would it have worked before and not now?