MyBackupPro as well as Titanium Backup let you backup your Apps and Settings including some system settings. Just be mindful about restoring system settings on different ROMs due to possible changes but Apps should be safe, even if there is a new version, the settings should transfer over. The backup with Rom Manager is a full NAND backup, that doesn't restore to a new rom, that restores everything including the ROM. So that is just something to have in case a new rom didn't turn out like you wanted and you wished you could go back!
