I searched the registry and couldn't find "4501," I tried a couple task reminders today and noticed that setting Start/Due displays the reminder properly. I am 99% sure that this 01/01/4501 is basically a "None," because that's what the Start/Due should be saying if I have not selected anything for them (only a timed reminder, not date, so date would be empty).
I can't be the first one to ever experience this, though?!