Well I definitely had an issue with alarms. It didn't go off the last 2 mornings lol.

I have it set for 6am. I went to bed around 10:30pm. I woke up around 6:15am and when I turned the phone on it showed 10:30 (from when I had it on last), then it quickly updated to 6:15am and the alarm went off.

The Clock on HTC Home will always update after you wake it. The clock is running but the today app is asleep. The real issue is the alarm which should trigger directly off the clock (not what HTCHome displays). So if you think you hav a fix test it with an alarm not by looking at the clock.

Note that "UNINSTALLS" don't always undo all the fiddling they did in the registry (I should know, I've written many install/uninstall programs that didn't :)). The only TRUE uninstall is a Hard Reset for some applications (probably most).

My wife's is brand new, she just go it, no programs installed on it. Her alarms don't work, her clock updates after a while, AND she doesn't get incoming calls untill she turns on the screen. This is really bad. Any solutions?

get another one

That is a different issue and there is another thread on here about not getting calls/sms/alerts while the phone is in standby.

The alarm worked fine, I just set it for 5 minutes out and it went off like it should have.

I agree but with previous builds I never experienced this problem. I am using 2.1 with the beta HTC Home Customizer. Like I said I might reflash mine device with the old Home plugin and test it.

What device and what rom is everyone using?