I played with the Pre for a little bit at the sprint store the other day.( My Touch Pro's internet died and i was hoping for a replacement at the store.)
The only thing I have to say that bugged me was that there was only ONE hardware button on the face of the phone (the home button on the middle bottom). I guess I'm used to having that end button on the bottom right and my dedicated phone button on the bottom left.
-all in all, its not a phone. but i think i'll be stickin with the Touch Pro for now...
But with all things, im sure it just takes some getting used to