I'd have to agree with gguruusa. You have to experiment and decide what's best for you. Some like an open Today screen, some seem to like to use every pixel for an icon or text of some sort. Some like a tabbed interface and don't mind scroll bars, some don't like either of those. The same goes with programs. Some like certain features, others could care less. The 3.5 kitchens are wonderfully easy to work with. Creating your own OEMs to include can be a little trickier, but not impossible (even for me!
). Reflashing your ROM is easy, and most times completely harmless. I know I've flashed an easy 40 times in the last few months trying various configurations, and trying to get some of my OEMs just right. Make sure you have a copy of the stock ROM, just in case. Whether you start with WM6, a pre-built 3.5 ROM, or cook your own, you'll become addicted to what you can do, always looking for that next capability!
Best of luck!
Brian