[ruskiyab]

Lots of options available.

For the G1 Stuff
Throttle lock will get you the lock you want, SPB Mobile shell 3 will get you a similar home screen that you can slide left and right with different widgets. You cannot run G1 applications on the Pro, however.
With that being said, there are people working hard to get android running on the Touch Pro, however at its current state, it cannot make phonecalls or use data. It does boot though.

For the iphone look:
There's obviously S2U2 for the lock screen, then you have iFonz or Wisbar Advance Desktop or iDiamond for the interface. iDiamond is the best looking one IMO, it runs off of the manila engine and is very smooth, however at it's current state it is nothing but an app luncher (as if the iphone UI is something more)