Exact same thing happened to me. I dont have anything installed. Took it out of my pocket last night to check my messages and the screen wouldnt respond. I could use the Dpad to navigate to the different screens, but the touch screen wouldnt work. Soft reset with no changes. So I hard reset just in case it was a software glitch, bug, conflict.
After the hard reset it went to that "align screen" display, and of course I cant align the screen cause the screen is still not responding to touch
I'm taking it to the Sprint store this evening. I think my build date was 10/26. I do have the raised D pad issue as well, but never addressed it with Sprint. So I guess I can kill two birds with one stone. Glad i synced before I did the hard reset.