http://www.wmexperts.com/articles/ho..._registry.html
http://wiki.xda-developers.com/index...5_Tweaks_Other
No need to remove the SD card. In fact you might want to backup to it before you start.
MAKE NOTES! You probably won't crash your phone if you're careful but you may want to manually undo your changes and it's mighty easy to forget what you did.