After 3 days of full use. I too have experienced some negative aspects of 3.35 compared to a very fast 2.17 with 1.40 radio.
I get lag in IE, certain system redraws of icons, menus. They used to be instant, now once in awhile usually if you don't softreset daily, after a few hours of use, memory does not get returned to the heap, and system slows to a crawl...