I have three of these spots, also in the bottom left quadrant. Initially I assumed it was because my screen always pressed against the back of my leather pouch, but I changed my mind when I noticed a similar spot on my friend's Mogul, which he keeps in his pocket. It's very likely the cause of this is a component behind the screen, like some have mentioned in posts above.
Either way, it doesn't bother me very much. I've grown to live with it now.
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