It's listed as a possible bug in the first post, but I'm running HTC Home 2.0.??? and I haven't had any issues with PIM Backup 2.5. I don't backup everything on my phone however, just stuff I can't restore via WMDC when I hook my phone back up to my PC, so I don't know if it's another item that's getting backed up that would cause an issue or not, but I haven't seen anything to suggest that they are incompatible.
EDIT: found a "bug" the OEMizer listing in BuildOS_config.txt displays it in BuildOS as ImageConverter instead of OEMizer. So this:
Code:
MenuExt=ImageConverter,Tools,Tools\SplashTools\OEMizer.exe,
Should be changed to this:
Code:
MenuExt=OEMizer,Tools,Tools\OEMizer.exe,