Truthfully, no, I don't notice any lag at all. Here's a rundown of what I've done to my phone, in case you're interested in the comparison:
-- Hard Reset
--
Touch Pro 2 Cleanup (my own set of hacks, see link for details... it DOES install the ATI D3D driver but not the GFXBOOST... still don't know what that is)
-- Contact Changer (doesn't do anything but convert all contacts to First Last instead of Last, First)
-- Facebook
-- Bing Search (replaces Live Search)
-- .NET Compact Framework 3.5
-- Font Pack (a collection of Windows fonts that I frequently need)
-- PHM RegEdit
--
S2U2 2.04 (see link, post #3 for customized version ... all settings configured for battery-friendly but functional settings ... preconfigured for RawBuffer mode)
-- Spb Screenshot applet
-- Total Commander
I also switch between TF3D and Spb Mobile Shell 3.0.1.
Literally, the only issue I have is with S2U2 not functioning in Landscape properly after a soft reset.
The subject of this thread. I don't really want to hijack this with a graphics driver debate, but if you like, I'll take this to another more appropriate thread and discuss in great detail (just not my cleanup thread either, lol).