I disagree with anyone who says a full charge/discharge is bad. I've never had a problem doing this and in your case, it couldn't really hurt.
Reflash the device with the stock Sprint ROM off of HTC's site and don't install any custom things. Just do these tweaks.
Then drain the battery 100% until it shuts itself off, charge it 12 hours, then try it... you may just fix the problem.
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