Remembered a post from some time ago on XDA-Developers regarding HTC phones and some registry settings that supposedly improve the touch sensitivity. Some claim it's a placebo, and many say it definitely improved their devices. I tried them out (2 keys) and I can't say I notice much difference between the medium setting and the maximum setting, but both do seem to help slightly over stock. (Which was already pretty damn good mind you). Anyway here is the thread:
http://forum.xda-developers.com/showthread.php?t=469865
And the reg keys involved are:
HKLM/Drivers/TouchPanel
DWORD Value: "PressureThreshold" = 10000 (Stock), 80866 (Medium), 4294967295 (Maximum) <All Decimal values>
HKLM/SOFTWARE/OEM/TFLOSettings
DWORD Value: "FingerPressure" = Doesn't exist (Stock), 80866 (Medium), 4294967295 (Maximum) <All Decimal values>
The FingerPressure value doesn't exist so you have to create a new DWORD value and enter the numbers above in Decimal not HEX.
Again I don't know how much if at all these help, but it seems to have a small positive effect with either set, so I'll likely just leave the medium values as I didn't see anything noticeable about the max values. Try for yourself and decide.